What are the 4 types of dengue fever?
Dengue is caused by a virus of the Flaviviridae family and there are four distinct, but closely related, serotypes of the virus that cause dengue (DENV-1, DENV-2, DENV-3 and DENV-4).
Which organs are affected by dengue?
Based on the fact that the liver is one of the main organs affected by dengue35,36,37,38 and that lungs and heart are also important sites involved with the severe disease13,37,39,40,41, samples from all these three organs were considered.
What is the confirmatory test for dengue?
Nucleic acid amplification tests (NAATs) Presence of virus by rRT-PCR or NS1 antigen in a single diagnostic specimen is considered laboratory confirmation of dengue in patients with a compatible clinical and travel history.
How much platelet count is normal in dengue?
Dengue fever can result in a drop in your white blood cell and platelet counts. The normal platelet count in the body ranges from 1.5 to 4 lacs, this can go down to as low as 20,000 to 40,000 in the case of dengue patients.
Why platelets are low in dengue?
When an infected mosquito bites a human, the dengue virus enters the bloodstream, it binds to platelets and replicates leading to multiplication of infectious virus. The infected platelet cells tend to destroy normal platelets which is one of the major causes for the drop in the platelet count in dengue fever.
Why is there liver enlargement in dengue?
Mechanisms of liver injury in dengue may be due to direct effects of the virus or host immune response on liver cells, circulatory compromise, metabolic acidosis and/or hypoxia caused by hypotension or localized vascular leakage inside the liver [5, 7, 10, 14, 22].
What is IgG positive in dengue test?
Positive IgM and IgG tests for Dengue antibodies detected in a sample means that the patient became infected with dengue virus within recent weeks.
How can I increase my platelets fast?
8 Things That Can Increase Your Blood Platelet Count
- Eating more leafy greens.
- Eating more fatty fish.
- Increasing folate consumption.
- Avoiding alcohol.
- Eating more citrus.
- Consuming more iron-rich foods.
- Trying a chlorophyll supplement.
- Avoiding vitamin E and fish oil supplements.
Which medicine is best to increase platelets?
Romiplostim injection is used to increase the number of platelets (cells that help the blood to clot) in order to decrease the risk of bleeding in adults who have immune thrombocytopenia (ITP; idiopathic thrombocytopenic purpura; an ongoing condition that may cause easy bruising or bleeding due to an abnormally low …
How much platelet count is normal?
A normal platelet count ranges from 150,000 to 450,000 platelets per microliter of blood. Having more than 450,000 platelets is a condition called thrombocytosis; having less than 150,000 is known as thrombocytopenia. You get your platelet number from a routine blood test called a complete blood count (CBC).
Why is AST and ALT high in dengue?
AST has various sources including the heart, striated muscle, erythrocytes, etc., apart from the liver, whilst ALT primarily is hepatic in origin[14,43]. Acute insult to these non-hepatic tissues by the DENV can result in higher elevations of AST when compared to ALT rise.
Why does WBC decrease in dengue?
This study may suggest that leukopenia in dengue fever may be caused by virus-induced destruction or inhibition of myeloid progenitor cells. Thrombocytopenia may result from by destruction of peripheral platelet or bone marrow megakaryocytes by viruses which consequently reduce the platelet production.
Which medications are used for the treatment of dengue?
Acetaminophen (paracetamol) is recommended for treatment of pain and fever. Aspirin, other salicylates, and nonsteroidal anti-inflammatory drugs (NSAIDs) should be avoided. Patients with dengue hemorrhagic fever or dengue shock syndrome may require intravenous volume replacement.
What are the signs and symptoms of dengue?
Dengue Symptoms in Adults. If any of your family members gets dengue fever,be careful about efforts to protect yourself and other family members from mosquitoes.
What are the causes of thrombocytopenia in dengue?
Thrombocytopenia occurs when platelet formation (thrombopoiesis) is insufficient to balance physiological or pathological platelet consumption. Thrombocytopenia may occur in patients with either mild or severe cases of dengue infection and are associated in the early days of dengue infection [ 1 ].
Is dengue a bacterial disease?
Dengue and Dengue hemorrhagic fever (DHF) are mosquito-borne viral disease caused by dengue virus, an Arbovirus (Arthropod borne Virus).