Who manufactures Massengill?
Massengill continued to operate as a family-owned pharmaceutical firm until it was acquired in 1971 by Beecham plc., itself later merged into SmithKline Beecham in 1989 and since 2000 into GlaxoSmithKline. On December 20, 2011, Massengill was sold to Prestige Brands for £426 million ($660 million).
What was sulfanilamide used for?
This medication is used to treat vaginal yeast infections. Sulfanilamide reduces vaginal burning, itching, and discharge that may occur with this condition. This medication is known as a sulfonamide antifungal. It works by stopping the growth of yeast (fungus) that causes the infection.
What is the connection between sulfanilamide and the creation of the Food and Drug Administration?
The drug and the deaths led to the passage of the 1938 Food, Drug, and Cosmetic Act, which increased FDA’s authority to regulate drugs. Sulfanilamide, a drug used to treat streptococcal infections, had been shown to have dramatic curative effects and had been used safely for some time in tablet and powder form.
What is sulfonamide tragedy?
Elixir sulfanilamide was an improperly prepared sulfonamide antibiotic that caused mass poisoning in the United States in 1937. It caused the deaths of more than 100 people.
Was Massengill discontinued?
The Massengill Medicated Douche brand name has been discontinued in the U.S. If generic versions of this product have been approved by the FDA, there may be generic equivalents available.
Where does the name Massengill come from?
Massengill Name Meaning English: habitational name from a place in North Yorkshire called Masongill. The surname has died out in England.
What are Sulpha drugs?
sulfa drug, also called sulfonamide, any member of a group of synthetic antibiotics containing the sulfanilamide molecular structure. Sulfa drugs were the first chemical substances systematically used to treat and prevent bacterial infections in humans.
How is sulfanilamide prepared?
The preparation method comprises the steps: adding n-acetylsulfanilyl chloride into ammonium hydroxide, reacting to obtain p-acetamidobenzene sulfamide, adding p-acetamidobenzene sulfamide into sodium hydroxide, hydrolyzing under the alkaline condition to obtain sodium sulfanilamide, reacting the sodium sulfanilamide …
Where is sulfonamide converted to Prontosil?
Prontosil is an azo-dye with the sulfonamide structure. In the human body, prontosil is metabolized into sulfanilamide under the action of cellular enzymes [3], which is shown schematically in Figure 1. Sulfonamides are the first successfully synthesized selectively toxic antimicrobial drugs [4,5].
What was in Elixir?
Elixirs are sweetened hydro-alcoholic (water and alcohol) liquids for oral use. Typically, alcohol and water are used as solvents when the drug will not dissolve in water alone. In addition to active drug, they usually contain flavouring and colouring agents to improve patient acceptance.
What does Massengill mean?
Massengill Name Meaning English: habitational name from a place in North Yorkshire called Masongill. The surname has died out in England. Similar surnames: Massingill, Massengale, Sasseville, Wassell, Tassell, Mansell.
